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HISTOLOGICAL IN VIVO STUDY: THE MECHANISM OF ACTION
Robert Weiss M.D.1, MV Dr. Jan Bernardy 2 1. Maryland Laser Skin, & Vein Institute, Hunt Valley, MD; 2. Veterinary Research Institute, Brno, CZ
  
 HIGHLIGHTS
- 92 % increase in average apoptotic levels in fat cells from 18.75 % at baseline, to 35.95 % 8 hours post 1 treatment (levels in the control subject remained stable).
 - The results show a link between fat cells apoptosis and elevated levels of free fatty acids released during supramaximal muscle contractions induced by the treatment.
 
- Blood analysis confirmed a rapid metabolic reaction after the treatment as supporting evidence of changes in the subcutaneous fat tissue. No safety risks were identified.
 
ULTRASONOGRAPHY STUDY: SUBCUTANEOUS FAT REDUCTION
 Bruce Katz M.D.1, Robert Bard M.D.2, Richard Goldfarb M.D.3, Aaron Shiloh M.D.4, Dilyana Kenolova M.D.5 1. Juva Skin and Laser Center, Manhattan NY, USA; 2 Bard Cancer Diagnostics, Manhattan, NY, USA; 3. Center for SmartLipo & Plastic Surgery, Langhorne PA, USA; 4. Shiloh Vein and Aesthetic Institute, Philadelphia PA, USA; 5. Dermasense Dermatology Clinic, Burgas, Bulgaria.
HIGHLIGHTS
 - 33 patients received four 30-minute treatments and were evaluated 1-month post-application.
 - Ultrasonography calculated fat thickness in multiple measurement points covering the whole abdomen.
 - On average 19.0 % (4.4 mm) reduction of fat was observed. The most significant reduction in fat (26.6 %) was observed subumbilical.
 
- High consistency with 0 non-responders; 21 out of 33 patients had greater than 15 % fat reduction.
 - 91 % satisfaction with treatment results.
 
MAGNETIC RESONANCE IMAGING (MRI) STUDY: SIMULTANEOUS FAT AND MUSCLE EFFECT
Brian M. Kinney M.D. FACS1, Paula Lozanova M.D.2 1. Plastic Surgery Excellence, Beverly Hills CA, USA; 2 Paula Fines Center, Sofia BG, Europe
  
 HIGHLIGHTS
- 22 patients were evaluated 2 months after four 30-min treatments.
 - Abdominal fat thickness was reduced on average by 18.6 % or 4.3 mm.
 
- Abdominal muscle mass increased on average by 15.4 %, coupled with a 10.4 % average reduction in diastasis recti.
 - Waist circumference decreased on average by 1.4 inches
 
WAIST CIRCUMFERENCE REDUCTION TESTED IN A MULTICENTRIC STUDY
 Carolyn I. Jacob M.D.1, Katya Paskova M.D.2 1. Chicago Cosmetic Surgery and Dermatology, Chicago IL; 2. Derma Vita Clinic, Sofia, BG
HIGHLIGHTS
 - 22 patients (lower BMI profile - average 23.8kg/m2) were treated in 4 sessions within 2 weeks.
 - Patient waist size was reduced on average by 4.37 cm at 3-month post-treatments.
 
- Patient photography captured a combination of muscle toning and fat reduction.
 - 96 % of patients were satisfied with treatment results.
 
